SNORA42: SNORA42 is a small nucleolar RNA that has been implicated in various cancer-related processes. Small interfering RNAs (siRNAs) targeting SNORA42 and KIAA0907 have been designed [PMC4966663]. Silencing SNORA42 has been shown to attenuate the tumorigenicity of lung cancer cells both in vitro and in vivo [PMC8658237]. The effect of SNORA42 expression on time to relapse and cancer-specific survival has been assessed using univariate and multivariate Cox proportional hazard models [PMC4966663]. Partial alignments of human SNORA42 on chromosome 14 have been illustrated in Figure 6 [PMC2206062]. It has been found that SNORA42 functions as an oncogene in hepatocellular carcinoma (HCC) by promoting the proliferation, invasion, and metastasis of tumor cells through accelerating cell cycle progression and inhibiting apoptosis [PMC8581050]. Furthermore, specific suppression of SNORA42 in cancer cells leads to apoptosis in a p53-dependent manner [PMC4427830]. Overall, these findings suggest that targeting SNORA42 may have therapeutic potential for the treatment of various cancers.