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hsa-mir-1265: Hsa-mir-1265 is a key microRNA (miRNA) that has been implicated in various diseases, including colorectal cancer, pancreatic cancer, and lung adenocarcinoma (LUAD) [PMC8544338] [PMC7962059] [PMC6380039]. It has been found to be upregulated in response to cadmium (Cd) stress [PMC4609416]. Hsa-mir-1265 has been shown to target the YWHAZ gene and may function as a sponge for hsa-mir-1265, leading to increased expression levels of YWHAZ and promoting tumorigenesis of LUAD [PMC6380039]. Additionally, hsa-mir-1265 has been identified as one of the miRNAs that target the MEG3 gene [PMC8695896]. It is also predicted to regulate several single nucleotide polymorphisms (SNPs) through its binding activity, including rs1050541 and rs1050540 in the TP53 gene [PMC8956157]. Furthermore, hsa-mir-1265 has shown differential expression patterns in various bioinformatic analyses and may be involved in regulating genes such as C2CD4A [PMC8520208] and miRNAs such as hsa-miR-579 and hsa-miR-1224-5p [PMC8956157]. Overall, hsa-mir-1265 is a versatile miRNA that plays a role in multiple diseases and regulatory processes.
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