SNORD112: SNORD112 is a C/D box small nucleolar RNA (snoRNA) that is part of a cluster of snoRNAs transcribed from the DLK1-DIO3 locus on human chromosome 14 (14q32) [PMC8976432]. The cluster includes SNORD113 1-9 and SNORD114 1-31 [PMC8976432]. SNORD112, along with some members of the SNORD113 family, is located in the intron of the MEG8 gene [PMC5641212]. It has been found that SNORD112 is ectopically expressed in acute promyelocytic leukemia (APL) [PMC6202974]. The expression of SNORD112 has also been observed in idiopathic membranous nephropathy and in post-therapeutic samples from patients with locally advanced cervical cancer (LACC) [PMC7441435] [PMC6900565]. Additionally, differential expression levels of SNORD112 have been identified when comparing relapsed and non-relapsed patients with acute myeloid leukemia (AML) [PMC7167781]. The association between CBs (Cajal bodies) and snoRNA genes, including SNORD112, has been investigated in HeLa cells, suggesting that CBs play a role in genome organization [PMC4802181]. It has also been observed that some variants of SNORD115 and SNORD116 snoRNA families have different expression patterns and putative targets in multiple myeloma (MM) [PMC3511933]. Furthermore, studies have shown that ectopic expression of certain snoRNAs from the DLK1-DIO3 locus can inhibit cell growth through specific signaling pathways, such as the retinoblastoma gene/p16 pathway [PMC5769367].