Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.
Homo sapiens (human) small nucleolar RNA, H/ACA box 11B (ENSG00000221102.1) secondary structure diagram

Homo sapiens (human) small nucleolar RNA, H/ACA box 11B (ENSG00000221102.1) URS0000673E8F_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

SNORA11B: SNORA11B is a small nucleolar RNA (snoRNA) that has been identified as a potential prognostic and therapeutic target in ovarian cancer [PMC10050728]. It is part of a signature of nine snoRNAs (SNORA11B, SNORA36C, SNORA58, SNORA70J, SNORA75B, SNORD105B, SNORD126, SNORD3C and SNORD89) that have been found to be downregulated in tumor tissues compared to normal tissues [PMC9119353]. The expression of these snoRNAs was tested in clinical tissues and found to be significantly decreased in tumor tissues [PMC9119353]. Additionally, the expression of snoRNA11B has been shown to have high accuracy for the identification of cholangiocarcinoma (CCA) versus primary sclerosing cholangitis (PSC) [PMC7140677]. Furthermore, a signature based on nine snoRNAs including snoRNA11B has been developed to predict the prognosis of ovarian cancer patients [PMC10001105]. The gene for snoRNA11B is located near other genes such as CALM1, NRDE2, PSMC1, RPS18P2 RPS6KA5 RNU7-30P C14orf159 on chromosome 14q32.11 [PMC5264598]. Overall, these findings suggest that snoRNA11B may play an important role in ovarian cancer and could potentially be used as a prognostic marker or therapeutic target.

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences
GGGGUGUGCUCAGAGCAGGGGGCCCGAAGAAUGCCUCCUCUGUUUACAACACACCCAAUAGGAAUCUGGGGUCAUUGUGACAAGGGACACAGAGCUUGUGACCUCCCUACAAACAAAUGCCCUACACAU

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

2D structure Publications