SNORD70: SNORD70 is a small nucleolar RNA (snoRNA) that has been identified as a transcript candidate based on read coverage peaks and annotation track analysis [PMC4682413]. It has been found to have overlapping binding sites with snoRD11 and snoRD56 on the 18S rRNA [PMC5612246]. SNORD70 is also known as HBII-234 and has been stably expressed across different tissues in mice [PMC6883285]. It has been used as an internal control in gene expression studies, such as in the assessment of miRNA expression levels [PMC7267729] and in qPCR-based assays [PMC7568261]. SNORD70 is involved in early ribosome biogenesis and dissociates before separation of the ribosomal subunits, indicating its role in early stages of ribosome maturation [PMC4288182]. It is one of the snoRNAs that function in early ribosome biogenesis, along with SNORD14, SNORD100, and SNORD20 [PMC4288182]. The curated coordinates for SNORD70 have been found to differ significantly from its known annotation [PMC4914119]. In addition to its role as a normalization control, SNORD70 has also been found to be expressed in a tissue-biased manner [PMC7568261].