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Homo sapiens (human) small nucleolar RNA, C/D box 100 (SNORD100) secondary structure diagram

Homo sapiens (human) small nucleolar RNA, C/D box 100 (SNORD100) URS000065DEBC_9606

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SNORD100: SNORD100 is a type of small nucleolar RNA (snoRNA) that has been studied in various contexts. In a heatmap analysis, it was found that SNORD100, along with SNORD14A, SNORD63, and SNORD59A, showed high expression in a low-risk group and low expression in a high-risk group [PMC8649667]. Depletion of DDX21 did not affect the distribution of snoRNAs associated with early pre-ribosomal complexes, including SNORD100 [PMC4288182]. SNORD100 is one of the snoRNAs with canonical ribosomal targets [PMC4914119]. The methylation guide sequence and C/D box of the sponge SNORD100 were well conserved [PMC3412847]. Both 5' and 3' end reads were recorded for several snoRNAs, including SNORD100 [PMC4159348]. In a study on colon cancer patients, it was found that reduced expression of snoRNAs including SNORD100 in tumors was associated with increased immune cell infiltration and could predict prognosis and immune landscape [PMC10050728]. Additionally, in exosomal RNA analysis, it was observed that snoRNA species such as SNORD6, SNORD69, and SNORD100 were among the most abundant RNA species [PMC9136061]. Overall, these studies highlight the importance of understanding the expression patterns and functional roles of snoRNAs like SNORD100 in various biological contexts.

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Sequence

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GCUGUACAUGAUGACAACUGGCUCCCUCUACUGAACUGCCAUGAGGAAACUGCCAUGUCACCCUUCUGACUACAGC

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2D structure Publications