SNORD2: SNORD2 is a small nucleolar RNA (snoRNA) that has been used as a reference for assessing miR-30c levels [PMC4860400]. It has also been used as an internal control for microRNA analysis [PMC4864075]. A synthesized SNORD2 oligoribonucleotide containing a single m6A modification has been used in miCLIP experiments [PMC6774519]. SNORD2 is one of several snoRNAs that have shown decreased levels in the plasma of lung cancer patients compared to healthy donors, suggesting its potential as a biomarker [PMC7140444]. Knocking down SNORD2, along with other snoRNAs, has been shown to significantly alter the splicing profile of their presumed pre-mRNA targets [PMC7038934]. Both the 5' and 3' ends of several SNORDs, including SNORD2, have been recorded in sequencing experiments [PMC4159348]. In various studies, SNORD2 has been found to be upregulated in response to exosome treatment following traumatic brain injury and in invasive breast cancer cell lines [PMC6044101] [PMC8445368]. In cancerous endometrial tissues, increased expression of SNORD116 and SNORD2 was observed, while expression of SNORD3 was decreased [PMC9256700]. Additionally, the snoRNA SNORD2 is found within introns of EIF4A2 and EIF3A genes [PMC8759569], and it is one of the most abundant snoRNAs detected in sequencing experiments [PMC7656686]. Overall, these findings highlight the potential role and significance of SNORD2 in various biological processes.