SNORA77: SNORA77 is a small nucleolar RNA (snoRNA) that is encoded on chromosome 22q11.2. It is a member of the H/ACA box snoRNA family and is also known as SNORA77 in the snoRNABase database [PMC3072320]. SNORA77 has been found to have tissue-specific effects in cancer and has been associated with different survival rates depending on the cancer type [PMC9803687]. It plays a role in the post-transcriptional modification of ribosomal RNAs (rRNAs) and is involved in improving the folding and stabilization of rRNAs [PMC6123486] [PMC7016268]. In non-small-cell lung carcinoma, higher levels of SNORA77 have been correlated with poorer overall survival [PMC9803687]. In kidney clear cell carcinoma, high levels of SNORA77 are associated with poor survival, while in kidney papillary carcinoma and liver hepatocellular carcinoma, high levels are associated with better survival [PMC6294694]. SNORA77 has also been identified as differentially expressed in patients with pseudoexfoliation glaucoma (PEXG) compared to control groups, suggesting its potential role in this condition [PMC9454646]. Overall, SNORA77 plays a significant role in various biological processes and its expression levels have been found to be associated with different diseases and outcomes.