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MIR524: MIR524 is a microRNA that is involved in various biological processes [PMC6193703]. It is part of the C19MC miRNA gene cluster, which consists of 46 miRNA genes [PMC6193703]. In breast invasive carcinoma, the expression of MIR524 is downregulated by an overexpressed EGFR/myc axis, leading to the activation of the TGF-β, Notch, and Hippo pathways [PMC9966483]. MIR524 also plays a role in regulating gene expression through its interaction with other molecules [PMC3938728]. It has been found to downregulate targets such as OLR1, CPEB4, and DUSP1 [PMC3938728]. Additionally, MIR524 is regulated by EGFR through recruitment of a repressive histone modifier to its promoter region [PMC7766154].
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