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hsa-mir-7705: Hsa-mir-7705 is a microRNA that has been studied in various types of cancer, including bladder urothelial carcinoma and gastric cancer. In bladder urothelial carcinoma, high expression levels of hsa-mir-7705 have been associated with shorter survival times [PMC5588142]. It has also been identified as one of the three best independent prognostic miRNAs for bladder urothelial carcinoma [PMC5588142]. In gastric cancer, hsa-mir-7705 has been found to be upregulated and to have a tumor suppressor role [PMC9816570]. It has also been shown to have a binding effect on hsa_circ_0061276, a circular RNA [PMC9816570]. Furthermore, the expression of hsa_circ_0061276 was significantly decreased after overexpression of hsa-mir-7705 in gastric cancer cells [PMC9816570]. In addition to its role in cancer, hsa-mir-7705 has also been implicated in normal breast tissue, where it was found to have allelic-specific binding to the reference allele of rs4808616 in the ABHD8 gene [PMC7018948]. These findings highlight the potential importance of hsa-mir-7705 as a prognostic factor and therapeutic target in various types of cancer.
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