SCARNA6: SCARNA6 is a small Cajal body-specific RNA (scaRNA) that belongs to the class of small nucleolar RNAs (snoRNAs) involved in RNA processing [PMC8952417]. It is a nucleolus component [PMC8952417]. SCARNA6 has a hybrid structure composed of both C/D box and H/ACA box elements and is known to bind to both C/D box core proteins and the H/ACA box specific Dyskerin [PMC4053766]. It is a member of the small Cajal body-specific RNA family [PMC8532824]. SCARNA6 has been found to be downregulated in various conditions, including during the exit from pluripotency in cells [PMC8713755], in cholesterol homeostasis regulation [PMC6839856], and in autism spectrum disorder (ASD) compared to controls [PMC4491207]. It has also been associated with stroke risk, as it is expressed in smokers before and after stroke [PMC6764500]. SCARNA6 has been detected in subcellular libraries, specifically within Cajal bodies, which are nuclear organelles involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs) or snurps [PMC4159348]. Overall, SCARNA6 plays a role in RNA processing and belongs to a family of RNAs with various functions.