SNORA14B: SNORA14B is a small nucleolar RNA (snoRNA) that has been identified in various studies. It has been found to be present in exosomes derived from pancreatic cell lines [PMC7461500]. In different exosome populations, SNORA14B has been shown to be enriched in Ep-CAM-Exos [PMC7461500]. SNORA14B, along with other snoRNAs, was detected using fluorescence in situ hybridization in pancreatic cell lines [PMC6360365]. It was also found to be present in CD63-positive exosomes isolated from the culture medium of pancreatic cell lines [PMC6360365]. SNORA14B has been investigated as a potential diagnostic marker for differentiating pancreatic ductal adenocarcinoma (PDAC) patients from control patients without pancreatic disease [PMC6360365]. In PDAC cells, SNORA14B was found to bind IGF2BP3 [Taniuchi et al., 2014a]. Additionally, SNORA14B was encapsulated in exosomes isolated from the serum of pancreatic cancer patients and conditioned medium of pancreatic cell lines [PMC9638531]. It has also been analyzed in circulating extracellular vesicles (EVs) from patients with PC and controls [PMC8200014]. The expression of SNORA14B has shown diagnostic potential for early-stage PDAC with an AUC value of 0.875 [PMC8750069] and 0.862 [PMC8424929]. Overall, these studies highlight the presence and potential diagnostic value of SNORA14B as a snoRNA associated with PDAC.