SNORD34: SNORD34 is a small nucleolar RNA (snoRNA) that is found in various species, including humans, turtles, alligators, ground-finches, bald eagles, zebrafinches, seriema birds, crows, and rifleman birds [PMC4378963]. It is located within the Rpl13a gene and is usually confined to a distinct single intron [PMC4234469]. SNORD34 has been found to be involved in various biological processes. In response to exposure to pro-inflammatory saturated fatty acids such as myristate and palmitate, SNORD34 expression is increased [PMC6710452]. It has also been implicated in the establishment of leukemic blasts in a subtype of leukemia [PMC8479548]. SNORD34 has been found to be downregulated in glioblastoma multiforme (GBM) cell lines and its depletion impairs clonogenic growth [PMC5747948][PMC7114786][PMC8629011]. Additionally, SNORD34 has been shown to bind to the nucleic acid-binding protein YB-1 in breast cancer cells [PMC5747948]. The expression of SNORD34 can also be affected by alternative splicing events involving adjacent introns [PMC4234469]. Furthermore, SNORD34 can be secreted by macrophages upon activation [PMC10050728]. Overall, SNORD34 plays a role in various cellular processes and its dysregulation has been implicated in different diseases.