SNORA33: SNORA33 is a C/D box small nucleolar RNA (snoRNA) [PMC3120706]. In HEK293T FUS KO cells, increased pseudouridylation at specific sites was accompanied by elevated levels of SNORA33 [PMC9941101]. SNORA33 is the genuine guide RNA for the pseudouridylation of a specific site in the 28S rRNA [PMC6984369]. SNORA33 has been associated with normal human aging [PMC7355415]. It is part of the H/ACA snoRNA gene cluster_739 [PMC7049693]. SNORA33, along with other snoRNAs, binds to EZH2, suggesting a role in rRNA processing [PMC7959742]. The interaction between EZH2 and SNORA33 was validated using a tagged RNA pull-down assay [PMC7959742]. SNORA33 displays similar changing patterns during early hypertrophy and is downregulated in certain conditions [PMC7959742] [PMC7461500] [PMC6036822] . Small RNA fragments derived from SNORA33 have been shown to produce measurable gene silencing effects, unlike other small RNAs derived from different sources [PMC7038934]. It is consistently male-biased in five tissues and has been identified as one of the exclusively male-biased genes along with STC2, ANGPTL4, TPSAB1, TPSB2, and SNORD genes[ PMC8455523]. The expression of SNORA33 is regulated by MRES-CoV infection and certain compounds[ PMC8618917].