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mmu-mir-5099: Mmu-mir-5099 is a microRNA that has been identified in various studies. It has been found to be upregulated in nonunion formation [PMC6641081], downregulated after HDAC4 inhibition [PMC9347038], upregulated after cerebral ischemia-reperfusion [PMC6798056], and downregulated with syncytial differentiation [PMC6366741]. However, qrt-PCR analysis could not show significant differences in gene expression rate for mmu-mir-5099 in nonunion formation [PMC6641081]. It has also been identified as one of the intersected miRNAs that are downregulated after HDAC4 inhibition and denervation [PMC9347038]. In the context of ischemic stroke, mmu-mir-5099 is one of the miRNAs that may serve as a biomarker for the third day after stroke onset [PMC6798056]. In syncytial differentiation, mmu-mir-5099 is significantly downregulated compared to trophoblast stem cells (TSC) [PMC6366741]. Furthermore, quantitative overlap analysis showed that mmu-mir-5099 is one of the oppositely regulated miRNAs between male and female profiles [PMC5179560]. These findings suggest that mmu-mir-5099 may play a role in various biological processes and could potentially serve as a biomarker for certain conditions. However, further research is needed to fully understand its functions and mechanisms of action.
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