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Homo sapiens (human) EAF1 antisense RNA 1 (EAF1-AS1) URS00004CF72D_9606

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EAF1-AS1: EAF1-AS1 is a long antisense non-coding RNA gene that is transcribed in antisense to EAF1 [PMC8762216]. It has been found to have different isoforms, some of which overlap with EAF1 and COLQ [PMC8762216]. EAF1-AS1 has been identified as differentially expressed in the brains of patients with Parkinson's disease, suggesting its potential involvement in the disease [PMC8762216]. Elevated levels of EAF1-AS1 have been detected in brain tissue samples from Parkinson's disease patients [PMC8762216]. Furthermore, eQTL up-regulation of EAF1-AS1 has been found to contribute significantly to the risk of developing Parkinson's disease [PMC8762216]. It has also been suggested that the deregulation of EAF1-AS1 may impact cardiac health and that future studies should investigate its regulatory impacts on EAF1 and the consequences on heart function and Parkinson's disease [PMC8762216]. In a study constructing a lncRNA-miRNA-mRNA interaction network, EAF1-AS1 was identified as one of seven lncRNAs involved [PMC8593877].

Genome locations

Gene Ontology annotations

Sequence

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AGGCACAAGGGAGGAAACAGAUCCAGAGAUGUCAUGGACUUGCCCAAGGGUGGAUCCUUAGGGUGUUGACUGCUGCAGUUUCAAGCUUACAUCUGCACCCUGCAGAAUCCAGAGGAAGAGACAAUGCCUGUUCCAGUGGCUCUCAAGAAAUUCUUUUCCAGCCAGGCAUGGUGGCUCAUGCCUGUAAUCCCAGCACUUUGGUAGGCUAAGUACUGGACUGGUUCUGAUGCUUUCACCAGUAACAGAAGCUCAAGCUGUGCUCAACUGACCCCCAAGGAUCCAGCCUGUCUCUGGGAUUCUCUAGGCCGUCCCGGAACUCCUACCAUGACCAGGGAAGUGUAGGGUUGGGGUUUGGCCCUAGACCUCUUAUCUGUCCACCUGCAAAGCCGUUUUAGUAACAGAUUUGGAAGCAAAGUAAGGUUUUUGAUGGCAGCUUGGUCACCAGCACUUCACUUAGGAACCAGUGCUGGGGAAGCGGAUGGGACAAUUUCUGAGUGUCUCCUGGGACAGACACAUAGGCCAUCGCUCCGCUAGGGGCAUGGAGGGUAUGUGUGGGUCAAAUUGCUAAAUAAUCUCCAAAGCUCAUUACAAUUAAUGGGCCGACCUAUUCCCCAAUGCCUGCUUUACUGGAAUUGUUCGGCCCCAUCCUUCCCCCACAGUAGAGUGAGCCAAUUUAAAUUUUCAAUGCAGUUCUUCAGCACUUGUGUGAUGAUAAUCAGCUUACAGGUCAAGGACCUUGGCAAUUCACCAAGGAGAUUGUUACAUUUGAGCAAUUCACCAUUACAAUCCAUGGGCCCAGAGGUUCCAGGAGCCUGCUUCCAGCCACCUCCACCAGGAUGCCAGGCAUAAACAGGGUCUCGCCAUGUUGCCCAGGCUGGUCUCAAACUCCUGGACUCAAGCAAUCCUCCCACCUCAGCCUCCCAAAGUGCUGGGAUUACAGGCAUGAGUCACCACAGCCAGCCCAGUACCUGCUUUUAAGGAGCUCAUACCGACCAGAGUUCAAGCAAAAAAAAAAAAAAAAAAAAAAGGUCUACUUAAACUUUGAAAGAUGAGAUUGUUCAAAAAUGACACGAGAAAAUCACCCAUCACCACUAAGUUAAAGACUUGAAUAUGUGAGAGUUCCAGAGCCUCAAACUCCUACUACAGUCACUGAUCCAUAACAUUUUCCUCUUGCAAUGGACUCCACGCCAAAGUAGCUCAGUCUUGC

Taxonomic tree

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Publications