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MIR7-3: MIR7-3 is a gene that encodes a mature miRNA called miR-7 [PMC7918072]. It is one of the three genes, along with MIR7-1 and MIR7-2, that produce mature miR-7 [PMC7918072]. MIR7-3 is located on chromosome 19q13 [PMC7918072]. In a study screening for mutations in miRNA genes related to the hypothalamus-pituitary-gonadal system, no mutations were found in MIR7-3 in patients with normosmic congenital hypogonadotropic hypogonadism (ncHH) [PMC6479198]. The expression of miR-7 in the human pituitary is mainly attributed to MIR7-3, which is located within the intron of the pituitary-specific gene PGSF1 (also known as MIR7-3HG) [PMC6479198] [PMC4600152]. The expression of miR-7 derives from three separate loci in the human genome: MIR7-1, MIR7-2, and MIR 73] [PMC6479198] [PMC4600152]. In humans, mature miR- 73] expression levels are enriched in various regions of the brain, particularly the pituitary gland [PMC4600152].
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