hsa-mir-1284: Hsa-mir-1284 is a microRNA that has been studied in various contexts. It has been cloned into the pRNAU6.1 vector for further analysis [PMC3470565]. Hsa-mir-1284, along with other microRNAs, has been found to target the IL12B 3'UTR sequence [PMC3470565]. However, in a luciferase assay, hsa-mir-1284 did not alter the activity of constructs containing the IL12B+1188A or IL12B+1188C alleles [PMC3470565]. Hsa-mir-1284 was selected for further investigation due to its proximity to a polymorphic site and its conservation among species [PMC3470565]. It has also been identified as one of the top-ranking microRNAs in certain studies [PMC7952531]. Hsa-mir-1284 has been studied in relation to diseases such as colorectal cancer and pancreatic cancer [PMC7962059] [PMC7962059]. It has also been validated through quantitative real-time PCR and found to be influenced by age [PMC6736862] [PMC6281647]. In other studies, hsa-mir-1284 was found to regulate a large number of predicted genes and was used in lentivirus constructs for experimental purposes [PMC4278335] [PMC6535428]. Finally, hsa-mir-1284 was one of the 18 miRNAs used to develop a predictive classification model for treatment response using a machine learning approach called Sequential Minimal Optimization (SMO) classifier. Other miRNAs included hsa-miR-185-5p and hsa-miR-20a-5p among others[ PMC8706948].