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Homo sapiens (human) OBI1 antisense RNA 1 (OBI1-AS1) URS000047DB4C_9606

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OBI1-AS1: OBI1-AS1, also known as PUF1-AS1 or RNF219-AS1, is an epigenetically deregulated long non-coding RNA (lncRNA) that is downregulated in glioblastoma multiforme (GBM) [PMC9624034] [PMC7193358]. Methylation of the CTCF binding site influences chromatin interactions and blocks the expression of OBI1-AS1 [PMC9624034]. Patients with low expression levels of OBI1-AS1 have a poor prognosis [PMC8905821]. OBI1-AS1 is downregulated after recurrence in GBM [PMC8905821]. CTCF plays a role in the modulation of OBI1-AS1 expression [PMC8905821]. OBI1-AS co-expressed genes are used for functional annotation [PMC8905821].

Targeting miRNAs 2 total

According to LncBase, this RNA is targeted by the following miRNAs:

Genome locations

Gene Ontology annotations

Sequence

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AUAGUUACUUGGGACAACAGUUUUAGCAGGGCUCUCUUUCUCCUUUCCUGAUCUCUCUGUUAAGCUGCCUGGCUCAUUUGAUAUCACAUCCAAAUUAUCAGCUGAUUGCUCUAUUGUUUUGGACAAUGCCCUGAAGCAUACCAAAAUGUGUCUGGAAUUGGUGGGUUCUUGGUCUUACUGACUUUAAGAAUGAAGUUGCGGACUUUUGCGGUGAUCCACCCUACCACAUAUUGUCUCCUAAUGGCCGUCCAGUUUAUCCUGGAGCCCUUGCAUGACACAGGCCUAUCGAAGCAUAGGAGAUGCCAAUAUUUUACCUCUUGGGUACUUUCUGUGUAGAAGAUUCAUAACAAGAACAAUACUUAUUCUGCAAUUCUUUAUAUAAAGCUCCAGAGGGAAGUGAGAAGGAUGUUCACUUGCUGGUGAGAGAAGGAGCUGGUUCCAUCCAUUACGCAGUCCCCUGGGAGCGCUAAAUGCAACUUUAUCUCAACGGGGAGUGGACGAUGAGCAGGACGUCGCUAGAGGGAAAGAGCCUCACUUCCCGUUUCCUUUGGCAGCGCCCUUUUCCCGACCUAAGGGAGCAGACCUUCGUUGGUUGGCGUGAGGACUGGCGGGAGAGGUUUUGUGCCAGGAUCCGCACUGUCUGGGGUGAACGCUCCUCACCUUUGACCUGAACCGCCAACUUCCCAUCCUCCACUUUUGGAGAGCGCGCCUGAUAGCUGCUGCCCACCUGGGCACUGACAUCCUCCUUCCGACCGGGUGCGGAGAAAGCACAAAGGAAGUAGACCAAGGAGACUGAAGGUGGUUAUGAAGACUGUGCAUCUCUGAGGACAUCUUAAACAAAGAUGACCCAAAUCUUUGAUCUUCAAAUAGUCGAUGUGAACUGCUUAACAAAAUGCCCUGGGAAAACUCUGUCUGAAACAAGCAGCUUGGGGGUUUGAUUUCAUUAGUUACUGGACAAGAACUGGAAUGGAGUGAAAAAUCUUCAUUCAUUUCUUGGUCAGAUGGAGAGAGGAGAAAAAAAGAAGUGGGUUUCCAUUCACUUCCAUUUUCUAACUGAUCAUUAGUUAGAGAACCUUUGGAAAGGUUUAGCUCAGUUUUUUCUUCCAACUUAUCAGGUUCCUCAAGAAAUUCACUGCCUUGAGAUGACUUUGAUAACCCAUCCAAAUCCAGUGACUUAAAACCGUUAUUACAAGGGCUCUUGCUGUUGUCUGACUCUGACAUCAUUGAAUCCAACUCAGAGAUUUUGUCAAGGUAAGCAGCAUCCAUCGAUGCUUCACUGGAUGUUCUUGUCCGGUUCAUUUCAAAAGAGCGAAUAGAAUUCAACCUUUUGGAUAAACAUAAGCCUGAUUUCUCACUCAAUUUUGAAGAUAUUUCUCCAACAGAAUUUGCUAUCGUGUUCCCCUCUGAACUUUCAAAAUCUAAGUUUUGGGCAUAGCUUGUGGAACAACAGUCCCAAAAUCCUGUCUUUGGGGAAGAAAAACAUUCUGAUUUCUUUUCAUUUUCACUUCUACUUAUAUCAUCUUCUGAAGAAUCUUUAUUAGAAACAUUUGAAGAAUCACAAAAAUCAUCAAACACCAAUUUUCUGAGAUGGUUUGAGUGCUUUUUGGAACCUCCUGCUUGGACCACAGAGCUCUCUCUAUUUUCUGGAGUACUGAGCUGAAGGCAACUAAGGGACAAAGGAGUACAAGGAGCUGGAAGAUCAUAAAGUUCUUCAUCUUUGUAGGGUACACAGUCACUUGGUUUAUUCCCCCAUUCUCUUUCCAAAUAAGUAUCCAUACUUGUAUCUGUCACAUCUAACAUUACUUCUACCUGUUCUUGAUAUAGGUCUUUGUUCUUAGAACAGUUAAGGUCUGCUUUGCUGGUACUUUCCUGCCUUGCAGAACUGGUGUCACACAGUCUGCUGCUGGAAGGCUUCGCUAGGUGAGAAGAACUGGAGGUGGAUGAGCCAGGCUGCUUUCUGGCACUAUCGCCUUGAUUCUUUGACACCACAUCCUCCUCACUGCCUUUGCUCCCUUUGCCAUCUGCAGAAAGUGCUGUCUGGCAAAUGGAAUUCAUAGCUUCUUUCUCUUCACUUGAAUUUUUUAGCUGUGCAACUUGAGAUUCUAGUUCCUCUAUAUACUUAUCACUUCGUUCCAGGGCUUUCUUGAGGCGAUUGGUUUCACGCUCAUACUGUUCUACUUUGGACUGAAGAGCAGCAACUGCAAACCUUCCAAACCUACAAAGAAUGGAAAGAUAGUUAAUCUUAUAACUCAAGCUUUUUUCUUUUCAAGGUUUGAGAGUGCAAACUGUCCCAGGCUAUUCUAAUUUCACCUAACAGUGACAUUUCAGACCACUCAAUGAGUAGGGCAAAUGCCAGAUGUAUAUUUUCAAAAAAUGGUUUCCCCACUUACAUAAUAAUAAACAUAUGAUAAUAAUAGC

Taxonomic tree

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Publications