gga-mir-10b: gga-mir-10b is a microRNA that has been studied in various contexts. It has been found to exhibit putative epigenetic silencing in a resistant line of breast cancer [PMC4404578]. Additionally, gga-mir-10b has been associated with differential chromatin marks and may contribute to increased susceptibility to Marek's disease in chickens [PMC4404578]. In the context of fat deposition, the expression level of gga-mir-10b has been found to increase significantly in the breast muscle of chickens after sexual maturity [PMC8002044]. It is one of the most abundant microRNAs, along with gga-miR-10a, and represents a large proportion of total reads in libraries [PMC5520360]. The upstream region of gga-mir-10b has been studied and its promoter-like elements have been predicted using bioinformatics tools [PMC6409792]. In dwarf chickens, gga-mir-10b is significantly upregulated in adipose tissue, suggesting a role in reduced adipogenesis compared to typical chickens [PMC7936154]. It is also one of the most abundant microRNAs detected in chicken somites [PMC3107184]. In MDV-infected cells, gga-mir-10b is increased compared to uninfected cells [PMC3472249]. Additionally, it has been found to be upregulated during MDV infection in the spleen [PMC7564597]. In vesicles derived from chicken cells, gga-mir-10b appears as one of the least abundant microRNAs detected [PMC7734234].