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hsa-mir-4492: Hsa-mir-4492 is one of the five most exosomal enriched miRNAs [PMC4713432]. It is associated with known susceptibility SNPs [PMC10061723]. Hsa-mir-4492, along with other miRNAs, has the potential to serve as a sensitive biomarker for HIV-1 infection in PBMCs, pending further validation in patient samples [PMC7556008]. In different comparisons, hsa-mir-4492 is downregulated in VP vs HIV-, EC vs HIV-, and VC vs HIV-, as well as in ART vs HIV- [PMC4865051]. The expression of CABIN1, a predicted target of hsa-mir-4492, increases in certain cell lines [PMC5361823]. Hsa-mir-4492 is one of the most significantly upregulated miRNAs and selected for confirmation along with other miRNAs [PMC4416288]. In a study focusing on multiple miRNAs, hsa-mir-4492 is among those examined for expression levels [PMC8487241].
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