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SNORA54: SNORA54 is a highly expressed singleton that belongs to the class of small nucleolar RNA, H/ACA box (SNORA) [PMC8178906]. It guides the modification of position U4539 in helix H93 of 28S RNA [PMC8178906]. SNORA54 is one of the seven bovine SNORAs that were identified as highly expressed singletons [PMC8178906]. It has also been found to be differentially expressed in individuals with autism spectrum disorder (ASD) [PMC6795181]. In addition, SNORA54 has been observed to be dynamically regulated during differentiation and development, with peak expression seen during different stages [PMC9102014]. SNORA54 has also been found to be differentially expressed in individuals with age-related macular degeneration (AMD) [PMC5813239]. Furthermore, SNORA54 has been associated with suggestive significance in genetic studies and survived multiple testing correction in some cases [PMC8169753] [PMC5534955] [PMC9036230]. It is worth noting that SNORA54 is involved in various biological processes, such as RNA splicing and clotting-related pathways associated with smoking-associated strokes [GeneCards] [GeneCards]
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Gene Ontology annotations
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