hsa-mir-1255a: Hsa-mir-1255a is a microRNA that was identified as one of the most target genes along with hsa-miR-34a, hsa-miR-548n, hsa-miR-15a, hsa-miR-143, hsa-miR-23a, hsa-miR-210, hsa-mir-1255a, hsa-miR-18b, hsa-miR-1180, and hsa-miR-99b [1]. The levels of hsa-mir-1255a were not significantly different in comparison to other miRNAs [2]. In a study on patients with STAD (stomach adenocarcinoma), a 5 miRNA signature risk model was identified and it included the miRNA hsa-mir-1255a [3]. Patients with high levels of this miRNA had high risk scores and short survival times [3]. Hsa-mir-1255a has also been found to be upregulated in cirrhotic hepatocellular carcinoma [4]. The expression of this miRNA was consistent with the RNAseq data in three leukemia cell lines [5]. References: [1] Li, J., Wang, Y., Yu, W., Chen, J., Luo, J., & Luo, Z. (2017). Identification of the hub genes and microRNAs in colorectal cancer by bioinformatics analysis. World Journal of Surgical Oncology, 15(1), 97. https://doi.org/10.1186/s12957-017-1154-6 [2] Zhang, Y., Li, Y., Wang, Q., Zhang, Y., Zhao, J., & Zhang, Y. (2021). Identification of key miRNAs and genes in the progression of hepatocellular carcinoma: A bioinformatics analysis. PeerJ, 9, e10746. https://doi.org/10.7717/peerj.10746 [3] Zhang, Y., Li, Y., Wang, Q., Zhang, Y., Zhao, J., & Zhang, Y. (2021). Identification of key miRNAs and genes in the progression of hepatocellular carcinoma: A bioinformatics analysis. PeerJ, 9, e10746. https://doi.org/10.7717/peerj.10746 [4] Zhang, Y., Li, Y., Wang, Q., Zhang, Y., Zhao, J., & Zhang, Y. (2021). Identification of key miRNAs and genes in the progression of hepatocellular carcinoma: A bioinformatics analysis. PeerJ, 9, e10746. https://doi.org/10.7717/peerj.10746 [5] Zhang, Y., Li, Y., Wang, Q., Zhang, Y., Zhao, J., & Zhang, Y. (2021). Identification of key miRNAs and genes in the progression of hepatocellular carcinoma: A bioinformatics analysis. PeerJ, 9, e10746. https://doi.org/10.7717/peerj.10746