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Homo sapiens (human) hsa-miR-320e URS00003B6B84_9606

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hsa-mir-320e: Hsa-mir-320e is a type of microRNA that is only present in primates and humans [42]. High expression of hsa-mir-320e has been associated with a negative prognosis and a high risk of metastasis in ovarian cancer [43]. Overexpression of hsa-mir-320e has been shown to promote B-cell proliferation by suppressing PTEN expression and promoting cyclin D1 expression [44]. In patients with non-small cell lung cancer, high expression of hsa-mir-320e, along with hsa-mir-320d, hsa-mir-320c, and hsa-mir-320b, has been linked to a negative prognosis and poor response to anti-PD-1 treatment [PMC7057418]. In the context of stromal cells, hsa-mir-320e has been identified as one of the differentially expressed miRNAs that are downregulated in both sets of comparisons [PMC7583725]. In human subjects, decreased levels of hsa-mir-320e in plasma have been suggested as a potential biomarker for the early detection of acute stroke [PMC4477423]. Furthermore, in individuals with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), decreased levels of hsa-mir-320e have been observed in extracellular vesicles compared to healthy controls [PMC7005890]. Hsa-miR-3960 is one miRNA that shows high expression levels along with hsa-miR-2115-5p, hsa-miR-8075, and hsa-miR6732p when comparing different types of adrenal tumors [PMC8139033]. Finally, HSA-MIR 630 is one exosomal miRNA that shows constitutive expression in nasal airway secretions in infants with respiratory viral infections [PMC9605003].

Genome locations

Gene Ontology annotations

Localisation

Sequence

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AAAGCUGGGUUGAGAAGG

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Publications