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Homo sapiens (human) microRNA hsa-mir-206 precursor URS0000389B41_9606

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MIR206: MIR206, a type of microRNA, plays a crucial role in the pathogenesis of ALS skeletal muscle impairment and regeneration by regulating the levels of PAX7, PAX3, and HDAC4, thereby affecting the balance between cell proliferation and differentiation [PMC5573384]. Myod can directly activate MIR206 to promote myogenic differentiation by inhibiting Pax3 and Pax7 [PMC8945367]. Additionally, MIR206 has been found to be downregulated in pancreatic cancer and functions as a tumor suppressor along with MIR96 and MIR126 [PMC7156858]. Furthermore, MIR206 or miR126 has been implicated in other studies as well [PMC6900182]. MIR206 is a type of microRNA that is involved in various biological processes. In the context of ALS skeletal muscle impairment and regeneration, it has been found to regulate the levels of PAX7, PAX3, and HDAC4. This regulation affects the balance between cell proliferation and differentiation [PMC5573384]. Myod is able to directly activate MIR206. This activation promotes myogenic differentiation by inhibiting Pax3 and Pax7 [PMC8945367]. In pancreatic cancer, MIR206 along with MIR96 and MIR126 are downregulated. These microRNAs function as tumor suppressors in this context [PMC7156858]. MIR206 or miR126 have also been implicated in other studies for their potential roles in various biological processes [PMC6900182].

Genome locations

Gene Ontology annotations

Sequence

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UGCUUCCCGAGGCCACAUGCUUCUUUAUAUCCCCAUAUGGAUUACUUUGCUAUGGAAUGUAAGGAAGUGUGUGGUUUCGGCAAGUG

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This sequence is found in 20 other species

Publications