SNORA25: SNORA25 is a type of small nucleolar RNA (snoRNA) that has been studied in various contexts. It has been observed that six SNORA25 paralogs in rhesus monkeys have multiple poly(A) sequences, indicating that these sequences may have undergone duplication events [PMC2832892]. SNORA25 has also been identified as a potential biomarker for the early detection of pancreatic cancer [PMC7313177]. However, an analysis of the 3'-terminal domain of human SNORA25 suggests that it does not form a structurally stable pseudouridylation pocket for positioning of 18S-Ψ814 [PMC6984369]. In a study examining exosomes isolated from cell culture medium, the presence of SNORA25 snoRNA was detected using a SYBR Green I assay [PMC6360365]. Furthermore, there was a correlation between the serum levels of SNORA25 and CA19-9, which is an established biomarker for pancreatic cancer [PMC6360365]. This suggests that SNORA25 may have potential as a noninvasive diagnostic biomarker for early detection of pancreatic ductal adenocarcinoma (PDAC) [PMC6360365]. In conclusion, SNORA25 is an interesting snoRNA with potential implications in cancer research and diagnostic applications.