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Homo sapiens (human) hsa-miR-518b URS00003676C9_9606

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hsa-mir-518b: Hsa-mir-518b is a microRNA that has been identified as an independent prognostic factor for bladder urothelial carcinoma [PMC5588142]. It has been found that hsa-mir-518b levels are low in placenta during FGR pregnancies, but these changes are not reflected in maternal plasma [PMC7708817]. In a study comparing different samples, hsa-mir-518b was found to be differentially expressed in bladder urothelial carcinoma [PMC8686203]. The expression of hsa-mir-518b was upregulated in both data sets of bladder urothelial carcinoma, but the expression of hsa-miR-486-5p was upregulated in one data set and significantly downregulated in another [PMC10116350]. Hsa-miR-518e and hsa-mir-518b, which are homologues of hsa-miR-518f, were found to be upregulated in hepatocellular carcinoma (HCC) [PMC5937522]. In a study investigating the expression of miRNAs, it was observed that hsa-mir-518b was upregulated more than twofold [PMC10083302]. Additionally, seven miRNAs were identified to overlap with hsa-mir-518b [PMC8566004]. References: [PMC5588142] [PMC7708817] [PMC8686203] [PMC10116350] [PMC5937522] [PMC10083302] [PMC8566004]

mRNA interactions 2 total

Genome locations

Gene Ontology annotations

Localisation

No annotated location

Sequence

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CAAAGCGCUCCCCUUUAGAGGU

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This sequence is found in 3 other species

  1. Gorilla gorilla gorilla ggo-miR-518b (MIR518B)
  2. Gorilla gorilla (western gorilla) ggo-miR-518b
  3. Pan troglodytes (chimpanzee) ptr-miR-518b
Publications