SNORD12C: SNORD12C is a small nucleolar RNA (snoRNA) that has been found to be reduced in tumors and increased in immune cells in patients with colon cancer [PMC10050728]. This snoRNA, along with six others (SNORD59A, SNORD63B, SNORD100, SNORD99, SNORD63, and SNORD19), has been identified as tumor immune infiltration-associated snoRNAs [PMC10050728]. These snoRNAs have the potential to predict prognosis and the immune landscape in colon cancer patients [PMC10050728]. In colorectal cancer, the levels of ribomethylation at specific sites (28S-Gm3899(3878) and 28S-Gm4623(4593)) are increased [PMC8677010]. This increase is attributed to the stabilization of the SNORD12C and SNORD78 snoRNP complexes by the host gene of SNORD12C, which encodes a long non-coding RNA called ZFAS1 [PMC8677010]. These findings suggest that SNORD12C plays a role in tumor immune infiltration and ribomethylation regulation in colorectal cancer [PMC8677010]. Further research is needed to fully understand the mechanisms by which these snoRNAs contribute to tumor development and immune response in colon cancer patients [PMC10050728].