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Homo sapiens (human) CD27 antisense RNA 1 (CD27-AS1) URS0000351B7C_9606

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CD27-AS1: CD27-AS1 is a long non-coding RNA (lncRNA) that is poorly understood in acute myeloid leukemia (AML) [PMC8131722]. Its expression, function, and molecular mechanism in AML remain unclear [PMC8131722]. However, it has been found that CD27-AS1 can increase the expression of PBX3, a transcription factor involved in AML development [PMC8131722]. This increase in PBX3 expression is achieved through the sponging of miR-224-5p by CD27-AS1 [PMC8131722]. In conclusion, CD27-AS1 is an lncRNA that plays a role in AML by regulating the expression of PBX3 through miR-224-5p sponging. However, further research is needed to fully understand the expression, function, and molecular mechanism of CD27-AS1 in AML.

Genome locations

Gene Ontology annotations

Sequence

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ACAGGAAAGGGCCCUGACAAGAGGAUGGGACUGCAGUUGUGGCUGCCAGGUCUCACUCUCCCUUGGAUGGUCGGCGGGGUGGGGGUGGAGGCCAGGGCUGUAGUGCAGCUCCCGCAGGUGCUGGCUCAGGGGGAGCAGGCAGGCUCCGGUUUUCGGUAAUCCUCCUGGAUGGGGAUGGUGCUGCCCUCCUCCUCCCUGGGGCAGCUGUAAUGACAAGGCUCUGCAGGCUCCACAGGACUUUCUCCUUUGUCUGCAGAAGGAGAUCCGAUGAGUCUUGGCCAGCAGUGGGGGCAGGGGGAGACGGGAGAAGGAGAUGGGUAGAGGCGGGUGCGCUUGGGGGAGGGGUGUCAGGAGCACGCCAGCUAAGGGGAGAGAAGGGGUAGGACCAAGGCUGGUGAAGUGGAGCUGGUGGGUUUCAGUGAGAUUCCAGGCGUGGGCAGUGGGGUUGAGCCAGUGGGGUGUGGUGCAGGGGCAGGACCGGAGGCCUGUGUUCUGUCUCUUACUUGAUCUAUAUUUCCUUCGUUGAUGGAGGAACAGGGCCCCGGCCAGGGUGAAAACAAGGAACAUUCCAGAGAAGAUCACAAGGAUGCGAAUAAAAUCGGAGCUGCACAGGGAUCUUUGGGCUGUAAUAGGAGGGGACACACAGGGGUUAGGGGAGGGUCUAGCCCUUGGCUCCCUCAGCCCAGCCCUCCUGUCACCUUGCCUCUCCCCUUUCCCCCACCUUAUUCUAUCCCACCCGCCACCGUUGGCCAACUCCUCUCCUAAACAGUGGACUCUGCUUUUUCCCCUCCUCUUAUCCCUAAUCCUAGGAGCUUUCUGUCUGGCUUCCCUCCUGGCCCCUCGUGUAUGCAUUCUCUCUAGCGGUGGGGAUUAAGGAGAAAACUCACGUGGCCAGUGGGUAGAGAGAGUCCGGGCAGGCAGCUGCCUGAAGUCAGCCAGAGUCUGCAUGUGCCCAGCUGUCCUGGCCUCCAGCAUCUCUGGAAAAACAGAGACAGAAUGAGUAGCAGCAGGGGACCCCAUAGGGCACAUCUGAAGGCCUGAGAGGUGCUGGAUGGGAUGGGAAGGCAGAAACAGGCUGACCUUAUCUAGGGGUAGGAGUGGGGAGUACUGGUUGGGGUAUCACCGCUACCCCACGUGAUGGCACAGAGAGUUGCCUGGAACUUACCACUGACAUAAGGUUGGAGUGCAGUGGCACGAUCUCGGCUCAGUGCAACCUCCGCCUCCUGAGUUCAAGUGAUUCUCCUGCCUCAGCCUCCCUAGUAGCUGGGAUUACAGGACAAGGAGAGGGACAAAUUCCUUCUUGGCAUCCUUAUGGCCCUGUGACCUGCUAAUGAAUGCUGACUCUGAGUUGCUACUAGAAUUUGGUUUCCUUGUGGCUUCCCAGGAAUUGGUCUCACUCUGCUCACUCUGUCUCCCAAGCUGGAGUGCAGUGGUACAGUCACGGCUCACUGCAGCCUCCACUUCCUGGACUCAAGUGAUCUUCUCACUUCAGCCUUCUGAGUAGCUGGGACUACAGCCCCCUCUGCAGCUCUUCAUGGGGGUCCACUCAAGUCAGAAGCCACAUUUGGGUGUGAUUCAGAGAGCUGUUUAUGCAAAACCAGCUUUGUCACCAUCAGGCAAGGCACCUGAAUUCCCACCGCAGAGAGUGUUGUGGCCGUGAGGACUUUUCUGUCACCAGCCAUUUCCAGGUAGACCCAGUGUAAUCACAAGCAUCCUUGUAAGUGGCAAAGAGGCAGAGGAGACAGCGCCAGAGAGGCAGCUGCAUGAGAAGGAUCAAGAUGUUGCUGACUUUGAAGUUGGAAGAAGAAGGCCAUGAGCCUCAGUAUGUGGGCGGCUUCUAGAAGCUGGAAGGGGCAAGGAGAUGGAUUUGACCCUUCAGCCUCCAGGGGCAGCUGUACCUGCCAUCACUGAUUGUAGCCUGGUGAGGCCUGUUUUAGACUUCUGACCUGUAGAGCUGUAACAUAAUACAUUUGGGUUGUUUUCAACCACUAAGUUUGUGGUAAUUUGUUGUAGCAGCUGUAGAAAAUGAAUACAUAUGAAUCCUCUGGCAUUUGUUUGAGAUUUGCUCUAUGGCCUAGUAUGUGGUUGUAAAUGUUCCAUCUGUGCCUGAAAAAAUGUAUAUUUCUAAUUCAGUAGUCUCUGCUUUUUUUUUUUAUUUUGUACCCCAUCAAUAAAAUGAUUUUCAGCAUGUAUCCCCAAAUAAACAAUAUUUUAUUUAUUGAUUGAUUGAUAAACAGACAUGUUUAAUGAUAGCUUGCUUUUCACAGAGGUGACUUCGGAGACUUCUAAUCUAUAAUCCAGGAGUAUAUAACCAUGCAGCACAGACCAAUUAGUCACAUGUAAAAUAAACUAGAUUCUUACCAC

Taxonomic tree

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Publications