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MIR17: Finally, grapefruit-derived nanovectors have been successfully used to deliver therapeutic MIR17 to the brain [PMC8067521]. Both double-knockdown lines, MIR17,18 and MIR17,g18-1, exhibited significant reductions in shoot surface area compared to the wild type and single mutants [PMC8528425]. This shoot growth impairment was not observed in any of the single mutants [PMC8528425]. The levels of STAT3, a protein involved in various cellular processes, are primarily regulated by MIR17, miR20a, miR19a, BRCA1, NF-KB1, ETS1, and ATF1 [PMC8627999].
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