MT-TV: MT-TV is a mitochondrial gene that encodes for tRNA valine [PMC5559820]. In a study, PBMCs collected after immunization with MT-TV or placebo were re-stimulated with overlapping peptides of DENV-1 and DENV-2 proteins [PMC5751980]. The study found that the T cell response in CM, assessed by IFN-γ ELISPOT, showed epitope preference and magnitude [PMC5751980]. The MT-TV mutation was suppressed using the non-cognate leucyl tRNA synthetase [PMC3927954]. Mutations in the 16SrRNA gene (MT-RNR2) have been associated with hypertrophic cardiomyopathy and myopathy [PMC7657662]. SLICE analysis suggested that chondrocytes expressing ASPN + MKI67– (Chond_5) have higher differentiation potential compared to chondrocytes expressing MT-TV + LGALS1– (Chond_3) [PMC9272381]. In tumor epithelial cells, MT-TV expression was found to be low or non-existent in patients without MT-TV mutations [PMC9380328]. Overexpression of mitochondrial aaRS (AARS2 or FARS2 tRNA synthetase) was explored to suppress the MT-TV mutation [PMC3927954]. PCR amplification and ultra-deep sequencing were used to assess mtDNA SNVs in a 4,767 bp mtDNA fragment spanning various genes including MT-RNR1, MT-RNR2, and MT-TV [PMC5121427]. Normal epithelial cells from adjacent tissues showed low expression of wild-type alleles of the MT-TV gene [PMC9380328]. Differential expression analysis identified several genes including protein-coding genes (MT-ND1, MT-ND2, etc.), rRNAs, and tRNAs (including MT-TV) as differentially expressed [PMC7934845].