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Homo sapiens (human) small NF90 (ILF3) associated RNA F (SNAR-F) secondary structure diagram

Homo sapiens (human) small NF90 (ILF3) associated RNA F (SNAR-F) URS000028A228_9606

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SNAR-F: SNAR-F is a genetic element found on human chromosome 19 [PMC3045588]. It is part of a larger segment of approximately 1.9 Kb [PMC3045588]. Through BLAT searches of the human genome, it was found that SNAR-F is present in the first repeat on chromosome 19 [PMC3045588]. This suggests that SNAR-F has evolved from a genetic element similar to those found in macaque and orangutan [PMC3045588]. The segment containing SNAR-F, along with a DEAH box polypeptide 34 (DHX34) gene, make up the H, I and A/B/C/D duplicons [PMC3045588]. To trace the dispersal of SNAR-F from its parent locus on chromosome 19, PCR was conducted on Great Ape genomic DNA and it was found that all African Great Apes contain SNAR genes, with a shorter element present in orangutan [PMC3337139]. Further searches revealed two orthologous segments separated by approximately 1.9 Kb on chromosome 19 of the rhesus macaque genome, with a triplicate tandem repeat demarcated by Alu sequence in between them [PMC3337139]. The syntenic repeat pattern is also present in the human genome, but with SNAR-F located in the first repeat instead of the truncated element found in orangutan and macaque. It was concluded that this element containing SNAR-F is likely to be the ancestor of snaR genes [PMC3337139].

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Gene Ontology annotations

Sequence

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CCGGAGCCAUUGUGGCUCCGGCCGAUUGCGCCGGCCCUCGGGCCCUCAGGGAGGCGAGGGUGUGAGGGUACAGAGUUCGAGGCCAACUUGGUCCACAUUGGUAGGAAAAAAAAAAUUUUUUUU

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2D structure Publications