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SNORD83B: SNORD83B is an orphan C/D box snoRNA that has been found to have various functions in gene regulation. It has been shown to reduce the stability of NOP14, SRSF3, and RPS5 [PMC7093170]. Additionally, SNORD83B has been found to regulate gene expression by binding to target mRNAs, revealing an unexpected function of snoRNAs [PMC7416809]. SNORD83B is one of the snoRNAs that have unexpected interactions with mRNAs and can control the steady-state levels of target mRNAs [PMC6798851]. It can be synthesized and expressed from the intron of the SNHG5 gene [PMC6848142]. SNORD83B has also been shown to have no meaningful KRAS binding activity [PMC6848142]. Furthermore, it stabilizes the levels of target mRNAs such as NOP14, RPS5, and SRSF3 [PMC8508363]. The expression signature of snoRNAs in CHIKV-infected HEK293T cells showed upregulation of SNORD83B among others [PMC9967650]. It has also been found to have interactions with multiple mRNAs affecting their stability [PMC9226514]. The downregulation of SNORD83B can affect mRNA targets by modulating their steady-state levels [PMC8162545]. LIGR-seq identified multiple novel interactions between SNORD83B and mRNAs as well as its function in controlling mRNA levels [PMC8969105][PMC5389715][PMC7140444][ PMC9644009][ PMC6248267][ PMC7038934].
mRNA interactions
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Genome locations
Gene Ontology annotations
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