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Homo sapiens (human) small nucleolar RNA, C/D box 50A (SNORD50A) secondary structure diagram

Homo sapiens (human) small nucleolar RNA, C/D box 50A (SNORD50A) URS00002524EE_9606

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SNORD50A: SNORD50A is a small nucleolar RNA (snoRNA) that inhibits the interaction between Fip1 and SVL pre-mRNA [PMC5587809]. It has been observed that SNORD50A and SNORD50B RNA binding to K-Ras inhibits K-Ras oncogenic function in various tumor types [PMC5386738]. The elevated expression of three selected mRNAs upon SNORD50A depletion has been confirmed through RT-qPCR analysis [PMC5587809]. SNORD50A and SNORD50B, located at 6q14.3 hg19 position chr6:86,387,011-86,387,376 within the introns of the SNHG5 gene, have been reported to directly act as tumor suppressors in breast cancer [PMC6789762].

Genome locations

Gene Ontology annotations

Sequence

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UAUCUGUGAUGAUCUUAUCCCGAACCUGAACUUCUGUUGAAAAAAAAAAACUUUUACGGAUCUGGCUUCUGAGAU

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2D structure Publications