MIR26A1: MIR26A1 is a microRNA that has been implicated in various biological processes and diseases. It has been found that the rs7372209 T allele in MIR26A1 is associated with an increased risk of endometriosis, while the reference C allele is protective against endometriosis development. However, these associations were not significant after Bonferroni correction [PMC5363543]. In aggressive chronic lymphocytic leukemia (CLL), downregulation of EZH2, a gene involved in cell survival, is induced by overexpressing MIR26A1. This suggests a pro-survival role of EZH2 in aggressive CLL and an indirect effect of MYC reduction on the levels of negative regulators such as MIR26A1 [PMC6773411]. In CLL patients, there is a negative correlation between the expression of EZH2 and its negative regulators like MIR26A1 [PMC6773411]. Additionally, MIR26A1 has been found to be hypermethylated and silenced in CLL patients, leading to higher levels of EZH2 [PMC5652802]. It has also been shown that MIR26A1 can regulate TET1 at the transcriptional level by modulating the levels of EZH2 at the TET1 promoter [PMC5652802]. Overall, these findings highlight the role of MIR26A1 in various diseases and its interaction with genes like EZH2 and TET1.