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mmu-mir-125a: Mmu-mir-125a is a microRNA that inhibits the proliferation of hepatocellular carcinoma, laryngeal squamous cell carcinoma, endometrial cancer cells, and increases stem cell quantities by targeting BAK1 [Bi et al., 2012; Jiang, 2011; Sun et al., 2017; PMC6829453]. It is also involved in the impairment of autophagy function in Ewsr1 knockout MEFs and mice by reducing the expression of the Uvrag gene [PMC4989891]. In addition, mmu-mir-125a is one of the most abundant miRNAs expressed in mice cortex samples [PMC6206094]. Mmu-mir-125a belongs to a group of miRNAs that are overexpressed during the development of primordial germ cells, along with mmu-miR-17-92 cluster, mmu-let-7, and mmu-miR-9 [PMC9505168].
References:
Bi et al., 2012: https://pubmed.ncbi.nlm.nih.gov/22848692/
Jiang et al., 2011: https://pubmed.ncbi.nlm.nih.gov/21660939/
Sun et al., 2017: https://pubmed.ncbi.nlm.nih.gov/28572517/
PMC6829453: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829453/
PMC4989891: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989891/
PMC6206094: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206094/
PMC9505168: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505168/
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