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mmu-mir-137: Mmu-mir-137 is a microRNA that has been studied in various contexts. It has been shown to be differentially expressed in BM-infiltrating and primary tumors [PMC4537015]. Mmu-mir-137 has also been used in transfection experiments, where a mimic of mmu-mir-137 was transfected into cells [PMC4506960]. Reverse transcription reactions and real-time PCR have been used to measure the expression of mmu-mir-137 [PMC4288926]. Mmu-mir-137 has also been studied in the context of its binding site on the CDC42 3'-UTR and its role in preventing binding to targets [PMC4648110] [PMC5905159]. It has been found that mmu-mir-137, along with other miRNAs, targets genes such as Luzp1 and Mtmr4 [PMC9106358]. Primer sequences have also been designed for mmu-mir-137 for further analysis [PMC2854370]. Mmu-mir-137 is one of the highly expressed miRNAs in neuronal cultures and is not differentially regulated [PMC2759968]. The expression level of putative mmu-mir-137 target genes has been found to be altered in various brain regions such as mPFC, striatum, thalamus, hippocampus, and cerebellum [PMC6667145]. The target genes of mmu-mir-137 have also been predicted using multiple databases [PMC6667145]. Hsa-miR-137 is strongly expressed in humans while mmu-miR-137 is strongly expressed in mice brain tissue. MiR-665 is not well characterized yet. MiRIDIAN miRNA mimic negative control was used as a control for experiments involving mmu-miR124a and mmu mir 37 mimics. The microRNAs used in the study were purchased from Ambion, Inc. [PMC9169915] [PMC3462785] [PMC2443372] [PMC2904378].
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