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hsa-mir-1293: Hsa-mir-1293 is a microRNA that has been observed to have a tumor suppressor role [PMC7352268]. In a study, the levels of hsa-mir-1293 derived from extracellular vesicles (EVs) were found to gradually increase after tumor removal until follow-up, but were significantly decreased in the metastatic group [PMC7352268]. This suggests that hsa-mir-1293 may play a role in inhibiting tumor growth and metastasis [PMC7352268]. Additionally, a 16-miRNA signature, which includes hsa-mir-1293 along with other miRNAs (hsa-mir-2116, hsa-mir-4161, hsa-mir-3942, hsa-mir-4435, hsa-mir-1307, hsa-mir-1254, hsa-mir-582, hsa-mir-5690, hsa-mir-4713, hsa-mir939 ,hsa -mir -421 ,hsa -mir -335 ,hsa -mir -4677 ,hsa -mir -4754 and has mir 4746), has been found to have the ability to classify lung adenocarcinoma (LUAD) pathological stages similar to combinations of 42 or 26 miRNAs [PMC7138293]. This suggests that the presence or absence of these miRNAs can potentially be used as biomarkers for LUAD staging [PMC7138293]. Overall, these findings highlight the potential importance of studying and understanding the role of microRNAs like hsa mir 1293 in cancer progression and as potential diagnostic or therapeutic targets.
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