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Homo sapiens (human) hsa-miR-126-5p URS00001D69F6_9606

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hsa-mir-126: Hsa-mir-126 is a microRNA that has been studied in the context of lung cancer. The primers used for quantitative PCR to detect hsa-mir-126 were provided as follows: forward primer 5′-ACAGTTCTCTCGTACCGTGAGTAAT-3′ and reverse primer 5′-AAAGGTTGATCTGCTCTCTCTCTC-3′ [PMC5529898]. These primers were used to amplify hsa-mir-126 in lung cancer tissue samples [PMC2764731]. The down-regulation of hsa-mir-126 was observed in the lung cancer tissue, suggesting a potential role for this microRNA in the development or progression of lung cancer [PMC2764731]. The reverse primer used for quantitative PCR was 5′-GGAACGTTCACGAATTTG-3′, and the forward primer was 5′-ATTGGAACGATACAGAGAGATT-3′ for human RNU6, which served as a control [PMC5529898]. These primers were used to detect and quantify hsa-mir-126 expression levels in lung cancer tissue samples. The down-regulation of hsa-mir-126 suggests that it may play a role as a tumor suppressor or have other regulatory functions in lung cancer development [PMC2764731]. Further research is needed to fully understand the mechanisms and implications of hsa-mir-126 dysregulation in lung cancer.

mRNA interactions 4 total

Genome locations

Gene Ontology annotations

Localisation

Sequence

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CAUUAUUACUUUUGGUACGCG

Taxonomic tree

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This sequence is found in 45 other species

  1. Alligator mississippiensis ami-miR-126-5p
  2. Anolis carolinensis (green anole) aca-miR-126-5p
  3. Bos taurus (cattle) bta-miR-126-5p
  4. Callorhinchus milii Cmi-Mir-126-P2-v2_5p (mature (guide))
  5. Canis lupus familiaris cfa-miR-126
  6. Cavia porcellus (domestic guinea pig) Cpo-Mir-126-P2-v2_5p (mature (guide))
  7. Cervus elaphus (red deer) cel-miR-126*
  8. Chiloscyllium plagiosum microRNA cpl-miR-126*
  9. Chrysemys picta bellii (western painted turtle) Cpi-Mir-126-P2-v2_5p (mature (guide))
  10. Chrysemys picta cpi-miR-126-5p
  11. Columba livia Cli-Mir-126-P2-v2_5p (mature (guide))
  12. Cyprinus carpio ccr-miR-126-5p
  13. Danio rerio dre-miR-126a-5p
  14. Dasypus novemcinctus Dno-Mir-126-P2-v2_5p (mature (guide))
  15. Echinops telfairi Ete-Mir-126-P2-v2_5p (mature (guide))
  16. Equus caballus (horse) eca-miR-126-5p
  17. Gadus morhua (Atlantic cod) gmo-miR-126-5p
  18. Gallus gallus gga-miR-126-5p
  19. Gekko japonicus Gja-Mir-126-P2-v2_5p (mature (guide))
  20. Haplochromis burtoni (Burton's mouthbrooder) abu-miR-126-5p
  21. Ictalurus punctatus ipu-miR-126b
  22. Lepisosteus oculatus (spotted gar) Loc-Mir-126-P2-v2_5p (mature (guide))
  23. Macaca mulatta Mml-Mir-126-P2-v2_5p (mature (guide))
  24. Maylandia zebra (zebra mbuna) mze-miR-126
  25. Microcaecilia unicolor Mun-Mir-126-P2-v2_5p (mature (guide))
  26. Microcebus murinus (gray mouse lemur) mmr-miR-126
  27. Monodelphis domestica (gray short-tailed opossum) mdo-miR-126-5p
  28. Monopterus albus (swamp eel) Mal-Mir-126-P2b-v2_5p (mature (guide))
  29. Mus musculus mmu-miR-126a-5p
  30. Neolamprologus brichardi (lyretail cichlid) nbr-miR-126
  31. Nomascus leucogenys (northern white-cheeked gibbon) nle-miR-126
  32. Oreochromis niloticus (Nile tilapia) oni-miR-126
  33. Ornithorhynchus anatinus oan-miR-126-5p
  34. Oryzias latipes (Japanese medaka) ola-miR-126-5p
  35. Pundamilia nyererei pny-miR-126
  36. Python bivittatus pbv-miR-126-5p
  37. Rattus norvegicus rno-miR-126a-5p
  38. Salmo salar (Atlantic salmon) ssa-miR-126-5p
  39. Scyliorhinus torazame Sto-Mir-126-P2-v2_5p (mature (guide))
  40. Sus scrofa (pig) ssc-miR-126-5p
  41. Taeniopygia guttata (zebra finch) Tgu-Mir-126-P2-v2_5p (mature (guide))
  42. Tetraodon nigroviridis Tni-Mir-126-P2b-v2_5p (mature (guide))
  43. Tor tambroides miR-126b-5p
  44. Xenopus laevis (African clawed frog) xla-miR-126-5p
  45. Xenopus tropicalis (tropical clawed frog) xtr-miR-126-5p
Publications