hsa-mir-488: Hsa-mir-488 is highly expressed in various regions of the nervous system, including the amygdala, temporal lobe, globus pallidus, cerebellum peduncles, cerebellum, caudate nucleus, whole brain, parietal lobe, medulla oblongata, prefrontal cortex, occipital lobe, hypothalamus, thalamus, subthalamic nucleus, cingulated cortex, pons, and spinal cord [PMC2635472]. It is also expressed in the fetal brain and in non-neuronal tissues such as the adrenal gland and adrenal cortex [PMC2635472]. Hsa-mir-488 has been found to have binding sites in a circular RNA called hsa_circ_0001649 for several other microRNAs including hsa-miR-203a and hsa-miR-127 [PMC7497355]. In various studies on different diseases and conditions such as schizophrenia and hepatocellular carcinoma (HCC), hsa-mir-488 has been found to be differentially expressed [PMC4863087][PMC7271455][PMC2707367][PMC6921333][PMC4046763]. It has also been shown to interact with viral genomes such as HCV RNA [PMC5511817]. Additionally, the human CYP1A1 gene has been found to have binding sites for hsa-mir-488 in its 3'UTR region [PMC5220472]. In liver cells with HBx expression (a viral protein), hsa-mir-488 was found to be upregulated [PMC5352919].