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hsa-mir-487a: Hsa-mir-487a is a microRNA (miRNA) that has been found to be differentially expressed in various biological contexts. In a study comparing the expression of C14MC miRNA across different histological grades, hsa-mir-487a was one of the miRNAs that showed significant differential expression between grade II and III [PMC6061222]. In another study, hsa-mir-487a was identified as one of the miRNAs whose expression differed between pre- and post-therapeutic patients with osteosarcoma [PMC6959019]. Additionally, hsa-mir-487a has been detected in the microRNA expression profile of sperm from patients with asthenospermia, and it is predicted to target the gene Wfdc3 [PMC5530988]. Furthermore, hsa-mir-487a has been found to have an over-represented binding site among ARGs in NP differentiation [PMC2764345]. The role of hsa-mir-487a in adipogenic differentiation was also investigated, where it was shown to target the gene EHHADH and be involved in amino acid metabolism pathways [PMC6471198]. The regulation of hsa-mir-487a by TGF-β1 was explored, and it was found that NF-kappaB (p65) had binding sites in the upstream region of its promoter [PMC4807160]. Overall, these studies highlight the diverse roles and regulatory mechanisms associated with hsa-mir-487a.
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