SNORD29: SNORD29 is a C/D box snoRNA that is located within the inside-out gene SNHG1, which also hosts several other snoRNAs [PMC4378963]. SNORD29 is part of a cluster of snoRNAs found on chromosome 11 [PMC4378963]. It is one of the snoRNA families that predate the last eukaryotic common ancestor (LECA) [PMC3511168]. SNORD29 demonstrates high expression and processing selectivity, as it is more abundant than SNORD28 [PMC4465335]. It has also been found to be upregulated in various studies, including in CHIKV-infected cells and in equine aging chondrocytes [PMC9967650] [PMC7461137]. The disruption of the gene encoding SNORD29 has been shown to inhibit the replication of certain viruses, such as HRV16 and HSV2 [PMC9967650]. The host gene SNHG1, which contains SNORD29, has been found to be located on chromosome 11q12.3 and also hosts other snoRNAs such as SNORD31 and SNORD28 [PMC9598326] [PMC7154078]. Additionally, reads derived from other intronic snoRNA families within the same locus have been detected, suggesting that multiple mature snoRNAs may be processed from this region [PMC4159348]. Overall, these findings highlight the importance and diverse roles of SNORD29 in various biological processes.