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mmu-mir-376a: Mmu-mir-376a is an up-regulated miRNA that has been identified as significant in several studies [PMC4989891] [PMC5745818]. It is one of the 15 up-regulated miRNAs identified by SAM analysis [PMC4989891]. In a study on mild traumatic brain injury (TBI), mmu-mir-376a was found to be upregulated, indicating its potential as a biomarker for TBI regardless of severity [PMC5745818]. Mmu-mir-376a has been compared to hsa-miR-376b, with mmu-mir-376a showing a higher similarity score (SQ) [PMC2500034]. However, the murine sequence of mmu-mir-376a is one nucleotide shorter and has different alignment characteristics compared to hsa-miR-376b [PMC2500034]. It should be noted that the seed sequence and editing of mmu-mir-376a are not conserved in murine tissue, leading to its exclusion from experiments involving murine tissue [PMC7452086]. Overall, mmu-mir-376a has been identified as an important miRNA in various studies and shows potential for further investigation in different contexts.
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