Caution, this is an AI generated summary based on literature. This may have errors, see here for more.
Please share your feedback with us.
dre-mir-16b: dre-mir-16b is a microRNA that is up-regulated in cold acclimation in fish [PMC6953832]. Our data showed that dre-mir-16b mimics could protect ZF4 cells under cold stress, suggesting its role in cold acclimation [PMC6953832]. In addition to dre-mir-16b, the expression of numerous other miRNAs, including dre-miR-100-3p, was significantly altered in cold acclimated cells [PMC6953832]. The exact roles and mechanisms of dre-mir-16b in cold acclimation remain unclear [PMC6953832]. However, it has been reported that the expression of miR-16 increases in platelets under cold-storage conditions [PMC6953832].
Furthermore, our study showed that both dre-mir-16b and dre-miR-100-3p contribute to cold acclimation by regulating cell survival under cold stress [PMC6953832]. The introduction of dre-miR-100-3p inhibitor and dre-mir-16b mimics protected ZF4 cells under cold stress, suggesting their involvement in supporting cell viability during cold acclimation [PMC6953832].
Overall, the findings suggest that both dre-mir-16b and dre-miR-100 contribute to the process of cold acclimation by regulating cell survival. However, further research is needed to fully understand their roles and mechanisms in fish during this process.
Genome locations
Gene Ontology annotations
Ancestor Chart
Loading ontology ancestors...
Failed to load QuickGO Ancestor chart
Sequence
Sequence features are shown above as colored rectangles.
Zoom in and click to view details, or
Reset