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Homo sapiens (human) hsa-miR-424-5p URS00000F0F49_9606

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hsa-mir-424: The disagreement concerning the role of hsa-mir-424 in pancreatic ductal adenocarcinoma (PDAC) and other cancers in the literature aroused our interest [PMC8174116]. Our computational target prediction analysis indicates that hsa-mir-424 does not directly bind to the 3'-untranslated regions of any genes associated with Nox2 or its regulation [PMC6356993]. In a study using intersection mapping, hsa-mir-424 was identified as one of three miRNAs, along with hsa-miR-375 and hsa-miR-196a, that showed overlap in their expression patterns [PMC7374920]. Furthermore, hsa-mir-424 was found to be highly expressed in peripheral blood mononuclear cells (PBMCs) and its expression was confirmed by quantitative PCR (qPCR) [PMC3189221]. The value of SCISSORâ„¢, a tool used for analysis, was demonstrated through studies on the prognostic effect of EPHB2 and its associated miRNA hsa-mir-424 in colorectal adenocarcinoma (COAD), as well as the association between CD4 and hsa-mir-155 with T-cell proportion [PMC8428296].

mRNA interactions 7 total

Genome locations

Gene Ontology annotations

Localisation

Sequence

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CAGCAGCAAUUCAUGUUUUGAA

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This sequence is found in 15 other species

  1. Bos taurus Bta-Mir-15-P1c_5p (mature (guide))
  2. Canis lupus familiaris (dog) Cfa-Mir-15-P1c_5p (mature (guide))
  3. Cavia porcellus cpo-miR-424-5p
  4. Dasypus novemcinctus dno-miR-424-5p
  5. Eptesicus fuscus efu-miR-424
  6. Equus caballus (horse) eca-miR-424
  7. Macaca mulatta mml-miR-424-5p
  8. Mus musculus (house mouse) Mus_musculus piRNA piR-mmu-49665523
  9. Nomascus leucogenys nle-miR-424
  10. Oryctolagus cuniculus (rabbit) ocu-miR-424-5p
  11. Pan paniscus ppa-miR-424
  12. Pan troglodytes (chimpanzee) ptr-miR-424
  13. Pongo pygmaeus ppy-miR-424
  14. Saimiri boliviensis boliviensis sbo-miR-424
  15. Sus scrofa (pig) ssc-miR-424-5p
Publications