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Homo sapiens (human) TGF-beta induced lncRNA (TBILA) URS00000D37A5_9606

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TBILA: TBILA is a long non-coding RNA (lncRNA) that is upregulated in patients with non-small cell lung cancer (NSCLC) and may serve as a potential diagnostic biomarker for this disease [PMC8503812]. Additionally, AGAP2-AS1 expression levels are also increased in NSCLC patients, suggesting its potential as a diagnostic biomarker [PMC8503812]. TBILA is upregulated by the TGF-β classical signaling pathway and plays a role in promoting the expression of human germinal center-associated lymphoma [PMC6322193]. It achieves this by binding with the Smad transcription factor complex, which enhances RhoA activation [PMC6322193]. These findings highlight the involvement of TBILA in NSCLC and its potential as a diagnostic biomarker for this type of cancer. Further research is needed to fully understand the mechanisms by which TBILA and AGAP2-AS1 contribute to NSCLC development and progression.

Targeting miRNAs 4 total

According to LncBase, this RNA is targeted by the following miRNAs:

Genome locations

Gene Ontology annotations

Sequence

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AUUACAGAUGGGCCAUGGGAGUUUUUCCACUACAGAUAUUUACGUUUAUAAAUCACGUUGUCUUCUUAGAAAAGUCAGAAGGAGGUUAAAACAGUCAAGCCACAGACCUGUAGAAAAUAUAGUAUCAACAACUCUCAAAUCUGAAAACAAACACCCAGUAACAAAAUGGGCAAAAUAUUUGAACAGACAUUUCACCAAAGGAACUAUACAGAUGAACAUUAAAAGAUGCUAAACAUUGUAGUUAUUAGGGAAGUGUAAAUCAAAUCCACAAUGGAACACUUUUACAUACUUAUUACAAUGGCUAUAAAACCCUGACAAUAUCAAGUAUGGCAAGGUAUGCAAAGCAACUGGAAGUCUCAUGCAUUGCUGAUGAGAAUGCAAAAUGACAGCCUUUUUGGAAAGAAGUGAUAAGGACAGAAGGCAGGGCUUUACUGGGUAGAAGAGGGUGGUUCACUGGCAAAGGUCCCACCCUCAAGCCUUGAAACCGAAGCCCUAAAUGAGAACAGUUAUCCCUGUUAUCCUGCCCAAAUGUUACUCUUUAGCCUGUCCAGCCCCCCUAUCCCGUGCCCAUAUAAACCCCAGACCUCAGCUGGCAGACAGACAAGCGGCUGAACAUCAAGAGGAGAAGAAGCAACUGAGUGUCAGAGAUGUGGCUUAACUUCAGGUGGCAUGACUUCAGGGAGGAGCCCGGCCAGAGACAGCAGACUUCAGGGAAAGGUCACUUUCUUCCUGCACCAUCCCCUUUGCAGCUCCCCUUCCACUGAGAGCCACUUCCACCAUUUAAUAAAAUCGUCCACAUCCAUCAACUUUCAAACCAUUCAUGCAACCUGAUUCUUCCUGGAUGCUGAACAAGAACCUGGGUACCAACAGGGCAGGGUGUAAAAGGCUGCCACCCUGACUCUCCAUUGAGUGGGUUAACACUUAGCUGUCCACGGAUGGCAACUGCUAAAAGAGCAUGAAUUGUAACACAUCCCUAAAUGCUGCUGUUGGGCUGGAGCCCAAAAGUGCUCAUCGAAGCCCUGGCACCCGCUUGCCUGCGUGCUCCCGCUCCCACAGAGAGUUUGAGCAUGGUGGUGGCCAAGUAAGUAGGCCACACCCCUGUCGCAAGUCCCGAGAAGGGGUCAAGGGAACUCUCCCAUCUCAGAAGUAUGGCAAUUUCUUAUAAAAUUGAACAUAGGGUUACUGUACAACCUGGCAAUUUCACUCCUAGGCAUUUAGCCAAGUGAAACUUAUGUCCUCUAAGACUGUGUGUACAAAUUUUUAUAUGUGCUUUACUCAUAAUAGCCGAAAUACCCUGGAAAUAGCCCAACUGAUCUUCAUUGAGUGAAUUGCUAAAUAAGCUCUGUGUUAUAUUACAUCCACACAACAGAAUCCUGACCAUCAUUGAAAAGGAGUGGACUAUUAAUACAUGCAAUAACUUGGAUCAAUCUCAAAUGCAUUACACUAAGUGAAAGAGACCAGACUUAAAGCCUACCUUCUGUGACAUUAGAGAUAAGGUGAAACCACAGGAACAGAAAACAUAUUAGUGUUGCCAGGAGCAAAAGGUGGGGGAGGUGUUGACUUUCAAAGCACAGGAGGAAAUUUUUUGUUGUUGUUCUUUAUCUUGAUUGUGUUAGUGCCCACAUGACUGUAUGCAUUUCUCAUAAUUCACAGAACUGUAUACUAAUAAGGGUGCACUUCACUGCACAUAAAUGAAUCUCAACAGACAAAAGGUUAAAAAAGAAAGAAAUCUCGGGACAGGAAUCAUGGAUUUUUGUAUUAUCCUUGUAUUUGAUGGUUGUUUCCAGUUUGGUCACUCAUCUGUUUGUUCAUUCCUUUAACAAGUAUGUGUCGAGUGCCUACUAUGUGCUGGGCACUGUAGGUUCAAUGGUAAGAAAAGCAGAUACAGGACUGCUCUUGUGAAGUUCCUUGAAAGAAAUAAAACAAAGUGCAAAAUA

Taxonomic tree

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Publications