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MT-TG: MT-TG is a mitochondrial gene that has been studied in the context of MFN2 cKO animals [PMC9046932]. In a study, it was found that several mitochondrial genes, including mt-Tl2, MT-TG, mt-Atp6, mt-Co2, mt-Cytb, and mt-Nd4, were upregulated in MFN2 cKO animals at PD 24 but downregulated at PD 52 [PMC9046932]. This suggests that the expression of MT-TG and other mitochondrial genes is dynamic and changes over time in MFN2 cKO animals. Additionally, it was observed that the induction of inflammatory cytokine expression was not observed in the hearts of MT-TG diabetic mice [PMC2682666]. This finding suggests that MT-TG may not play a role in the induction of inflammatory cytokine expression in diabetic mice [PMC2682666]. Further research is needed to fully understand the role and regulation of MT-TG and its implications in mitochondrial gene expression and diabetic conditions.
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