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hsa-mir-423: Hsa-mir-423 is a microRNA that has been studied in relation to various diseases. The genotype frequencies for hsa-mir-423 rs6505162 C>A polymorphism in the control group were found to be in Hardy-Weinberg equilibrium (HWE) [PMC3832359]. This polymorphism has been associated with a reduced risk of breast cancer and is significantly associated with overall and recurrence-free survival in colorectal cancer patients [PMC9281991]. In a study comparing low and high expression of hsa-mir-423, it was found to be differentially expressed and consistent with the findings of another study by Rothe et al [PMC4433233]. The other miRNAs that were differentially expressed in this study included let-7i, hsa-miR-379, and hsa-miR-422a [PMC4433233]. These findings suggest that hsa-mir-423 may play a role in the development and progression of various diseases. Further research is needed to fully understand its mechanisms and potential therapeutic implications.
mRNA interactions
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