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hsa-mir-506: Hsa-mir-506 is a microRNA that has been found to exert a growth-inhibiting function [PMC5226495]. In a study, several differentially expressed microRNAs (DEmiRNAs), including hsa-mir-506, were identified to be closely associated with 12 hub differentially expressed mRNAs (DEmRNAs) [PMC6781644]. Another study demonstrated that over-expression of hsa-mir-506 significantly inhibited the proliferation and metastasis of breast cancer cells [PMC7296691]. Furthermore, an interaction between KCNQ1OT1 and hsa-mir-506 has been identified in the plasma of patients with elevated glucose levels [PMC9451601]. In order to validate the expression of SLC7A8 and hsa-mir-506, a validation cohort consisting of 20 pairs of non-metastasis tissues (NMTs) and lung metastasis OS tissues (LMOTs) was enrolled [PMC9750666]. PCR assays were used to measure the expression levels of several endogenous miRNAs, including hsa-mir-506 [PMC2904378]. Additionally, hsa-mir-506 was found to be one of the top ten upregulated miRNAs in a study that examined differentially expressed miRNAs in breast cancer cells [PMC5072262].
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