hsa-mir-548o: Hsa-mir-548o is a microRNA that has been found to be upregulated in esophageal cancer tissues compared to normal esophageal tissues [PMC8325912]. It has been confirmed to downregulate CAMK1D, indicating its protective role [PMC6448084]. In patients with stomach adenocarcinoma (STAD), high levels of hsa-mir-1255a, hsa-mir-3687, and hsa-mir-9-3 were associated with short survival times, while high levels of hsa-mir-548o and hsa-mir-7-2 were associated with longer survival times [PMC6448084]. Hsa-mir-548o has also been identified as downregulated in glioblastoma and upregulated in cirrhotic hepatocellular carcinoma [PMC6448084]. In a study on STAD patients, a 5-miRNA signature (hsa-mir-1255a, hsa-mir-3687, hsa-mir-9-3, hsa-mir-548o, and hsa-miR7.2) was identified as an independent prognostic predictor of survival time [PMC6448084]. Hsa-mir-548o was found to be positively associated with overall survival time in STAD patients [PMC6448084]. It is worth noting that there are other miRNAs that are also up or down-regulated in various cancers [PMC3794036] and a prognostic panel for gastric cancer patients includes miRNAs such as hsa-mir-548o [PMC7692123]. Additionally, other human miRNA precursors, including hsa-mir-548o, have been found to be duplicated through miRNA sequence homology searches [PMC5959248].